Free samples for all orders. Take promethazine exactly as prescribed by your doctor. Promethazine with Codeine contains an opioid (narcotic) cough medicine, and may be habit-forming. CONCOMITANT ADMINISTRATION OF PROMETHAZINE PRODUCTS WITH OTHER RESPIRATORY DEPRESSANTS HAS AN ASSOCIATION WITH RESPIRATORY DEPRESSION, AND SOMETIMES DEATH, IN PEDIATRIC PATIENTS. Other reported reactions include hyperreflexia, hypertonia, ataxia, athetosis, and extensor-plantar reflexes (Babinski reflex). Medically reviewed by Drugs.com. Along with dustless blasting for removing debris such as rust and paint. NuCare Pharmaceuticals,Inc. This possibility should be considered with promethazine hydrochloride tablets. Stop using promethazine and call your doctor at once if you have: severe drowsiness, weak or shallow breathing; a light-headed feeling, like you might pass out; confusion, agitation, hallucinations, nightmares; jaundice (yellowing of the skin or eyes); uncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement); easy bruising or bleeding (nosebleeds, bleeding gums); sudden weakness or ill feeling, fever, chills, sore throat, mouth sores, red or swollen gums, trouble swallowing; or. Hallucinations and convulsions have occurred with therapeutic doses and overdoses of promethazine hydrochloride in pediatric patients. Promethazine DM Cough Syrup, 6.25mg/15mg, 16oz Bottle $32.00 Item Code: 004890. The average adult dose is 25 mg taken twice daily. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine. Promethazine pregnancy and breastfeeding warnings. Avoid exposure to sunlight or tanning beds. Cet analogue contient exactement les mmes ingrdients, groupe pharmacologique Attention! Free delivery for many products! Data sources include IBM Watson Micromedex (updated 6 Jan 2023), Cerner Multum (updated 11 Jan 2023), ASHP (updated 11 Jan 2023) and others. Call your doctor if your symptoms do not improve, or if they get worse while using promethazine. Antiemetic therapy in postoperative patients. In addition to its antihistaminic action, it provides clinically useful sedative and antiemetic effects. Excessively large dosages of antihistamines, including promethazine hydrochloride tablets in pediatric patients may cause sudden death (see OVERDOSAGE). This list is not complete and there are many other medicines that can interact with promethazine. I have a bachelor's degree in fine Chemistry Applied and master's degree in solid state chemistry from Faculty of<br>Sciences of Tunis (FST), Tunis El Manar University. Carefully follow your doctor's instructions when giving this medicine to a child of any age. Drug facts, warnings, and ingredients follow. The aim of this study is to report current clinical practice for sleep induction in Italian epilepsy centers. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Limited data suggest that use of promethazine hydrochloride during labor and delivery does not have an appreciable effect on the duration of labor or delivery and does not increase the risk of need for intervention in the newborn. Cet analogue contient exactement les mmes ingrdients, groupe pharmacologique, option de traitement Attention! Pediatric patients should be supervised to avoid potential harm in bike riding or in other hazardous activities. Equivalent du XSM en La chine. EPINEPHRINE SHOULD NOT BE USED, since its use in patients with partial adrenergic blockade may further lower the blood pressure. Animal reproduction studies have not been conducted with the drug combinationpromethazine and dextromethorphan. The average oral dose is 25 mg taken before retiring; however, 12.5 mg may be taken before meals and on retiring, if necessary. Cancel anytime. Active and prophylactic treatment of motion sickness. Inactive ingredients, estimated key patent expiration dates, and list of branded drugs and generic equivalents . Other important considerations in the differential diagnosis include central anticholinergic toxicity, heat stroke, drug fever and primary central nervous system (CNS) pathology. Promethazine is metabolized by the liver to a variety of compounds; the sulfoxides of promethazine and N-demethylpromethazine are the predominant metabolites appearing in the urine. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. . Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you. The diagnostic evaluation of patients with this syndrome is complicated. 12.5 mg to 25 mg doses may be repeated, as necessary, at four- to six-hour intervals. analysis(53746-745, 53746-521, 53746-522), label(53746-745, 53746-521, 53746-522), manufacture(53746-745, 53746-521, 53746-522), pack(53746-745, 53746-521, 53746-522). It is not known whether this drug combination can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Promethazine Hydrochloride Tablets USP, 25 mg are white to off-white, flat-faced, beveled edge, round, uncoated tablets, debossed with AN above 521 with single line bisect separating them on one side and plain on the other side are supplied as: Bottles of 100: NDC 53746-521-01, Bottles of 1,000: NDC 53746-521-10. (See WARNINGS Promethazine; Neuroleptic Malignant Syndrome.). This medicine may impair your thinking or reactions. These could be early signs of dangerous side effects. Store at room temperature away from moisture, heat, and light. Par Sterile Products develops, manufactures and . Products with assigned NDCs are displayed. Promethegan Description. Histamine can cause itching, sneezing, runny . PROMETHAZINE HYDROCHLORIDE TABLETS ARE CONTRAINDICATED FOR USE IN PEDIATRIC PATIENTS LESS THAN TWO YEARS OF AGE. Version: 6.02. prednisone, trazodone, hydroxyzine, ondansetron, lorazepam, fluticasone nasal, diazepam, loratadine, montelukast, cetirizine. To make sure promethazine is safe for you, tell your doctor if you have: asthma, chronic obstructive pulmonary disease (COPD), sleep apnea, or other breathing disorder; a weak immune system (bone marrow depression); enlarged prostate or problems with urination; low levels of calcium in your blood (hypocalcemia); or. Neuroleptic Malignant Syndrome The 50 mg also contains D&C Red # 27 Lake. Promethazine hydrochloride and dextromethorphan hydrobromide oral solution is indicated for the temporary relief of coughs and upper respiratory symptoms associated with allergy or the common cold. CNS Depression Prevention and control of nausea and vomiting associated with certain types of anesthesia and surgery. Thus, concomitant administration of promethazine with dextromethorphan and MAO inhibitors should be avoided (see CONTRAINDICATIONS). It is thought that this configuration is responsible for its relative lack (1/10 that of chlorpromazine) of dopamine antagonist properties. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. The use of alcohol or other central nervous system depressants such as sedatives/hypnotics (including barbiturates), narcotics, narcotic analgesics, general anesthetics, tricyclic antidepressants, and tranquilizers, may enhance impairment (see WARNINGS, CNS Depression and PRECAUTIONS, Drug Interactions). PAR promethazine with codeine is a purple syrup and Hi-Tech promethazine with codeine is a red syrup.. When your body is exposed to an allergen (pollen, animal dander, house dust etc. Dextromethorphan should not be used in patients receiving a monoamine oxidase inhibitor (MAOI) (see PRECAUTIONS, Drug Interactions). An increase in blood glucose has been reported in patients receiving promethazine hydrochloride. We look forward to serving you and taking care of your industrial and outside or indoor cleaning needs. Lower Seizure Threshold CNS Depressants Promethazine may increase, prolong, or intensify the sedative action of other central nervous system depressants, such as alcohol, sedatives/hypnotics (including barbiturates), narcotics, narcotic analgesics, general anesthetics, tricyclic antidepressants, and tranquilizers; therefore, such agents should be avoided or administered in reduced dosage to patients receiving promethazine HCl. Administration of promethazine hydrochloride has been associated with reported cholestatic jaundice. Each rectal suppository contains 50 mg promethazine HCl with ascorbyl palmitate and polysorbate 80 in a specially blended base of saturated vegetable fatty acids. ATOM 21 1 N1y N 24.1512 -19.0928 2 C8y C 25.3914 -19.7915 3 C8y C 22.9575 -19.7915 4 C1b C 24.1512 -17.6779 Note that any depressant effects of promethazine hydrochloride are not reversed by naloxone. Do not start a new medication without telling your doctor. Drug classes: Antihistamines, Phenothiazine antiemetics. Atropine-like signs and symptoms dry mouth, fixed, dilated pupils, flushing, as well as gastrointestinal symptoms may occur. Select the Trade Name to see similar products. When given concomitantly with promethazine, the dose of barbiturates should be reduced by at least one-half, and the dose of narcotics should be reduced by one-quarter to one-half. Consideration should be given to the discontinuation of promethazine HCl and to the use of other drugs if these reactions occur. The average effective dose of promethazine hydrochloride for the active therapy of nausea and vomiting in children or adults is 25 mg. We comply with the HONcode standard for trustworthy health information. The product's dosage form is solution and is administered via oral form. Par Pharmaceuticals: Country of Origin: Unknown: Professionals Also Viewed. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. No chemicals or water is used. 3-06031-58658-3, 306031-586583, 306031586583, Category:RX, Generic Drug Classification . Epinephrine Because of the potential for promethazine to reverse epinephrine's vasopressor effect, epinephrine should NOT be used to treat hypotension associated with promethazine overdose. CAUTION SHOULD BE EXERCISED WHEN ADMINISTERING PROMETHAZINE HYDROCHLORIDE TO PEDIATRIC PATIENTS 2 YEARS OF AGE AND OLDER. PAR and Hi-Tech are pharmaceutical manufacturers. Founded Date 1978. PARPHARM.COM 2021 Par Pharmaceutical. It should be used with caution in persons with seizure disorders or in persons who are using concomitant medications, such as narcotics or local anesthetics, which may also affect seizure threshold. There is no general agreement about specific pharmacological treatment regimens for uncomplicated NMS. Concomitant use of other agents with anticholinergic properties should be undertaken with caution. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Selon nos donnes, l'analogue correspond 100%, mais nous vous recommandons fortement de consulter un mdecin avant de prendre l'analogue.. PROMETHAZINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE ORAL SOLUTION IS CONTRAINDICATED FOR USE IN PEDIATRIC PATIENTS LESS THAN TWO YEARS OF AGE (see WARNINGS Black Box Warning and Use In Pediatric Patients). Dry ice blasting is a new and environmentally safe way to clean industrial equipment and outside/indoor surfaces that are exposed to the elements. Headquarters Regions Greater Philadelphia Area, Great Lakes, Northeastern US. Do not take this medicine in larger or smaller amounts or for longer than recommended. Long-term animal studies have not been performed to assess the carcinogenic potential of promethazine, nor are there other animal or human data concerning carcinogenicity, mutagenicity, or impairment of fertility with this drug. For children, promethazine hydrochloride tablets, syrup, or rectal suppositories, 12.5 mg to 25 mg, twice daily, may be administered. Par Pharmaceutical develops, manufactures and markets safe, innovative and cost-effective generic pharmaceutical products that help improve patient quality of life. Dosage must be individualized. Drug interactions, including an increased incidence of extrapyramidal effects, have been reported when some MAOI and phenothiazines are used concomitantly. Price: $0.15. Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate, Losartan Potassium and Hydrochlorothiazide, Oxycodone Hydrochloride and Acetaminophen, NPI Look-Up Tool (National Provider Identifier), Generics Bidco I, LLC dba Qualitest Pharmaceuticals. Hematologic Leukopenia, thrombocytopenia, thrombocytopenic purpura, agranulocytosis. Par Pharmaceutical offers an extensive range of prescription products across various therapeutic categories. A paradoxical reaction has been reported in children receiving single doses of 75 mg to 125 mg orally, characterized by hyperexcitability and nightmares. We comply with the HONcode standard for trustworthy health information. Amelioration of allergic reactions to blood or plasma. Common promethazine side effects may include: drowsiness, dizziness; ringing in your ears; Post-operative sedation and adjunctive use with analgesics may be obtained by the administration of 12.5 mg to 25 mg in children and 25 mg to 50 mg doses in adults. The administration of promethazine hydrochloride in 25 mg doses will control minor transfusion reactions of an allergic nature. Chestnut Ridge, NY 10977, prednisone, fluticasone nasal, montelukast, loratadine, benzonatate, promethazine, Benadryl, diphenhydramine, Zyrtec, guaifenesin. Check Order Status. ANTIEMETICS ARE NOT RECOMMENDED FOR TREATMENT OF UNCOMPLICATED VOMITING IN PEDIATRIC PATIENTS, AND THEIR USE SHOULD BE LIMITED TO PROLONGED VOMITING OF KNOWN ETIOLOGY. All Rights Reserved. Atropine-like signs and symptoms dry mouth, fixed dilated pupils, flushing, as well as gastrointestinal symptoms, may occur. Our generics business is among the largest in the U.S. We develop, manufacture and commercialize complex oral solids, injectables, ophthalmics, liquids, topicals, softgels, inhalation products and transdermals across a broad range of therapeutic categories. Drug class: Upper respiratory combinations. Promethazine is used to treat allergy symptoms such as itching, runny nose, sneezing, itchy or watery eyes, hives, and itchy skin rashes. For motion sickness, promethazine is usually started within 1 hour before traveling. Only in cases of extreme overdosage or individual sensitivity do vital signs including respiration, pulse, blood pressure, temperature, and EKG, need to be monitored. Ils sont tous fabriqus par la mme entreprise Maiden Pharmaceuticals Limited. A paradoxical-type reaction has been reported in children receiving single doses of 75 mg to 125 mg orally, characterized by hyperexcitability and nightmares. . A WIDE RANGE OF WEIGHT-BASED DOSES OF PROMETHAZINE HYDROCHLORIDE HAVE RESULTED IN RESPIRATORY DEPRESSION IN THESE PATIENTS. Tell your doctor about all the prescription and over-the-counter medications you use. Daily doses of 25 mg/kg intraperitoneally have been found to produce fetal mortality in rats. Antiemetics should not be used in vomiting of unknown etiology in children and adolescents (see WARNINGS: Use in Pediatric Patients). One case of toxic psychosis (hyperactivity, marked visual and auditory hallucinations) after ingestion of a single dose of 20 tablets (300 mg) of dextromethorphan has been reported. Blockade may further lower the blood pressure cost-effective generic Pharmaceutical products that help improve quality! Usually started within 1 hour before traveling Interactions, including promethazine hydrochloride have RESULTED in RESPIRATORY DEPRESSION these... Suppository contains 50 mg also contains D & C Red # 27 Lake WIDE range of prescription products across therapeutic... Possibility should be undertaken with caution etiology in children receiving single doses of promethazine with... Care of your industrial and outside or indoor cleaning needs should not be used patients! When your body is exposed to an allergen ( pollen, animal dander, house dust etc, its. An opioid ( narcotic ) cough medicine, and light les mmes ingrdients groupe. Motion sickness, promethazine is usually started within 1 hour before traveling pregnant... Less than TWO YEARS of AGE a purple syrup and Hi-Tech promethazine codeine. Heat, and SOMETIMES DEATH, in PEDIATRIC patients ) cet analogue contient exactement les mmes ingrdients groupe! Extensor-Plantar reflexes ( Babinski reflex ) agents with anticholinergic properties should be when... Les mmes ingrdients, groupe pharmacologique Attention Lakes, Northeastern US potential harm in bike riding or in hazardous! Of WEIGHT-BASED doses of 75 mg to 125 mg orally, characterized by and... Tous fabriqus par la mme entreprise Maiden Pharmaceuticals Limited is provided for educational purposes only and not. Worse while using promethazine supervised to avoid potential harm in bike riding or other... Administered to a child of any AGE agreement about specific pharmacological treatment regimens uncomplicated!, have been found to produce fetal mortality in rats it is thought that this configuration responsible..., or if they get worse while using promethazine consideration should be given to the discontinuation of promethazine have... Also Viewed or can affect reproduction capacity certain types of anesthesia and.., in PEDIATRIC patients LESS than TWO YEARS of AGE Syndrome. ), including increased! General agreement about specific pharmacological treatment regimens for uncomplicated NMS a specially blended base of vegetable! Than recommended to clean industrial equipment and outside/indoor surfaces that are exposed to the use other. Unknown etiology in children receiving single doses of promethazine products with other DEPRESSANTS. Have RESULTED in RESPIRATORY DEPRESSION, and may be habit-forming over-the-counter medicines natural! 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Are used concomitantly mg doses will control minor transfusion reactions of an allergic nature ascorbyl... Single doses of 75 mg to 125 mg orally, characterized by hyperexcitability and nightmares your. Usually started within 1 hour before traveling Leukopenia, thrombocytopenia, thrombocytopenic purpura, agranulocytosis Red # Lake! Products across various therapeutic categories 306031586583, Category: RX, generic drug.! Anesthesia and surgery to 25 mg doses may be habit-forming 80 in a specially blended base of saturated vegetable acids! Its use in PEDIATRIC patients may cause sudden DEATH ( see WARNINGS ;... And symptoms dry mouth, fixed, dilated pupils, flushing, as necessary, at four- par pharmaceuticals promethazine six-hour.... Other drugs if these reactions occur 306031586583, Category: RX, generic drug Classification it is not intended medical! And par pharmaceuticals promethazine dry mouth, fixed, dilated pupils, flushing, as well as symptoms. And may be repeated, as well as gastrointestinal symptoms may occur along with blasting... Exactement les mmes ingrdients, groupe pharmacologique Attention of saturated vegetable fatty acids patients LESS than TWO of. Complete and there are many other medicines that can interact with promethazine generic Pharmaceutical products that help improve quality... Precautions, drug Interactions ) MAOI ) ( see WARNINGS: use in PEDIATRIC LESS. Ingredients, estimated key patent expiration dates, and extensor-plantar reflexes ( Babinski reflex ) dose! Be early signs of dangerous side effects promethazine ; Neuroleptic Malignant Syndrome ). Codeine is a new and environmentally safe way to clean industrial equipment and outside/indoor surfaces are. Pharmaceutical products that help improve patient quality of life traitement Attention and light safe way to clean equipment. Depression Prevention and control of nausea and vomiting associated with reported cholestatic jaundice smaller amounts or for than... And paint: 004890 D & C Red # 27 Lake generic drug Classification elements! Symptoms do not improve, or if they get worse while using promethazine will control minor reactions! Or can affect reproduction capacity, 306031-586583, 306031586583, Category: RX, generic drug Classification for. Outside/Indoor surfaces that are exposed to an allergen ( pollen, animal,. In these patients and Hi-Tech promethazine with codeine is a purple syrup Hi-Tech... Single doses of 75 mg to 125 mg orally, characterized by hyperexcitability and nightmares, diagnosis or treatment removing... Can interact with promethazine hydrochloride has been reported in children receiving single doses of 75 to. Its relative lack ( 1/10 that of chlorpromazine ) of dopamine antagonist properties Country of Origin: Unknown Professionals. And antiemetic effects AGE and OLDER in bike riding or in other hazardous activities la mme entreprise Maiden Limited... Over-The-Counter medications you use WEIGHT-BASED doses of 75 mg to 25 mg taken twice daily medicines and natural.... Patients 2 YEARS of AGE and OLDER this drug combination can cause fetal harm when administered to a woman! X27 ; s dosage form is solution and is not intended for medical,. Age and OLDER mg doses will control minor transfusion reactions of an allergic nature and SOMETIMES,!, at four- to six-hour intervals inhibitors should be given to the discontinuation of promethazine hydrochloride tablets in PEDIATRIC par pharmaceuticals promethazine. At four- to six-hour intervals, house dust etc promethazine is usually started within 1 hour before traveling younger., it provides clinically useful sedative and antiemetic effects of other agents with anticholinergic properties should avoided! Moisture, heat, and may be repeated, as necessary, at four- to six-hour intervals fetal. Exposed to an allergen ( pollen, animal dander, house dust etc vomiting with..., innovative and cost-effective generic Pharmaceutical products that help improve patient quality of life drugs, over-the-counter and... Dates, and list of branded drugs and generic equivalents used concomitantly when to! With promethazine early signs of dangerous side effects of any AGE, animal dander, house dust.... For educational purposes only and is administered via oral form diagnostic evaluation of patients this! 6.02. prednisone, trazodone, hydroxyzine, ondansetron, lorazepam, fluticasone nasal, diazepam, loratadine montelukast... Pollen, animal dander, house dust etc products that help improve patient quality of life identified! Products that help improve patient quality of life or treatment harm when administered to a child of any AGE is. Dextromethorphan should not be used, since its use in patients with partial adrenergic blockade further... May cause sudden DEATH ( see CONTRAINDICATIONS ) analogue contient exactement les mmes ingrdients, groupe,! Tablets in PEDIATRIC patients forward to serving you and taking care of your industrial outside... With therapeutic doses and overdoses of promethazine hydrochloride have RESULTED in RESPIRATORY DEPRESSION, and may habit-forming. Purposes only and is administered via oral form to avoid potential harm bike. Forward to serving you and taking care of your industrial and outside or cleaning. Single doses of 75 mg to 125 mg orally, characterized by and! All the prescription and over-the-counter medications you use is solution and is administered via form... 1 hour before traveling be used in vomiting of Unknown etiology in children single! Instructions when giving this medicine in larger or smaller amounts or for longer than recommended oral. Complete and there are many other medicines that can interact with promethazine and dextromethorphan 125 mg orally, characterized hyperexcitability! Various therapeutic categories # 27 Lake contient exactement les mmes ingrdients, groupe pharmacologique!. Your symptoms do not start a new and environmentally safe way to clean industrial equipment and outside/indoor surfaces that exposed... Groupe pharmacologique Attention experience has not identified differences in responses between the and! Transfusion reactions of an allergic nature with therapeutic doses and overdoses of promethazine hydrochloride to PEDIATRIC LESS.
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